TNOX-Aloha..
+++Also TNX-355 requires only twice monthly injections versus Fuzeon's twice daily.
Are these infusions or injections? I was under the impression TNOX's mab is infused...
I certainly think Fuzeon is going to eventually wind up on the shelf. TRMS and Roche have encountered many obstacles in marketing the drug, plus it's chemical synthesis/manufacturing is a BEAR, an absolute BEAR to produce. Fuzeon works, it just so unfriendly to patients. TRMS has recently announced they have two new fusion inhibitors in preclinic status shooting for once a week injection. There should be some great abstracts coming out this week from the CROI conference in Denver. TNOX, TRMS, PANC are presenting posters.
+++was a watch for possible immunosuppresive response.
I'm not surprised, it seems any mab that effects the immune system could be considered dangerous after the Tsyabri...I am following TNOX's clinical development, along with HGSI's mab. Duke University is testing PPHM's mab in preclinical studies right now for HIV, so I'm particularly interested in the how that is going to unfold.
Regards,
katie...