Biotech Values

[DewDiligence]

Re: 8w vs 12w treatment duration

Not sure I agree that physicians will be enthusiastic about prescribing an 8-week treatment regimen that is off-label or quasi off-label (i.e. not explicitly sanctioned or contra-indicated in the label). An additional 4 weeks of all-oral therapy does not seem unduly burdensome in exchange for reducing the risk of relapsing, particularly in treatment-naïve patients where GILD’s cocktail apparently does not require ribavirin.

I don’t expect third-payers to push for an 8-week regimen unless it is explicitly endorsed in the label for certain subgroups.