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Re: biotech_researcher post# 171587

Thursday, 12/19/2013 8:10:43 PM

Thursday, December 19, 2013 8:10:43 PM

Post# of 257268
I don't have the share numbers, but a good analog to consider would be Tasigna (bid) vs. Sprycel (qd) in second line CML. The biggest problem with this analog is that, IIRC, Tasigna launched substantially after Sprycel.

A more fundamental problem with looking for an analog, which I think Dew has spoken to before, is that we're talking about, in the scheme of things, a very short treatment duration, while compliance is usually thought of more on terms of chronic diseases. So while compliance might logically be worse for ABBV/ENTA, I don't know how important this will be to prescribers or payers, especially given how hard it would be to actually prove a difference in compliance between regimens.

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