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Re: DewDiligence post# 171178

Thursday, 12/12/2013 11:54:27 AM

Thursday, December 12, 2013 11:54:27 AM

Post# of 257266
ENTA
I do agree that GILD can at best hope to match ABBv/ENTA's efficacy, but i think it is a very high likelihood they will based on phase 2. In this scenario I do think ABBV can still compete and be the preferred regimen under some plans based on price as long as all other factors are more or less equal*. However sofosbuvir will always have to be available IMO to PI failures and this market - while modest - will almost completely go to GILD

The best case scenario for ENTA is that GILD's regimen doesn't measure up in terms of efficacy. However unlikely, it is a possibility, and then crazy things could happen to the stock prices of the respective companies

*There is a chance GILD could have comparable efficacy without ribavirin or with 8 weeks duration and ENTA's regimen requires ribavirin. If GILD can drop ribavirin and ENTA cannot this would present a worst case scenario for ENTA obviously, and then i think GILD has far more leverage with insurance plans. I don't think going from 12 to 8 weeks with ribavirin will have as large an impact on the commercial prospects as being able to drop ribavirin

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