I, patently silly, don't think vidpok45 added the following contents although he did say "A predicted 40 percent decrease in SAEs with a 15 mg. reduction in dose while maintaining efficacy is fantastic news if true."
– A 15 mg reduction in average daily dose intensity is predicted to lead to ~40% reduction in the risk of arterial thrombotic events – While predicted MCyR rates decrease with reduced dose intensity, substantial responses (predicted and observed) occurred at lower doses. In addition, pts who dose reduced after achieving MCyR were able to maintain response
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