Biotech Values

[bladerunner1717]

re: GERN

BTW - The argument being made by GERN et al appears to be that if they fix the root cause that that MUST fix the major QoL symptoms. But that is far from certain - as would probably be apparent if we could compare the Jakafi data vs the Imetelstat data on important symptoms effecting QoL. Fixing my broken frig won't unspoil the meat. Fixing my brakes won't unmangle my car.

Your metaphors are a bit skewed, if not downright screwy. The point is that if you fixed the brakes in the first place, your car wouldn't have gotten mangled. Or better yet, if the car is going to be totaled, then putting a new fender on it (jakfai, get it?) isn't going to save it from the junk heap.

Clark, no matter how many times nuere and I keep telling you that GERN didn't present the data--Tefferi did--you keep trying to trash GERN. You seem obsessed with this. I'll say it again, GERN didn't write the abstract, Tefferi did.

My problem is you and jq1234 and PGS is that all of you act as if the final data is in and the case is closed. Jq1234 is wrong: I can accept the data as is, but I believe that it is provisional. You either act as if the data is complete or you imply that Tefferi is fudging on the data or both (and you, Clark, keep bringing up GERN as being untrustworthy, which, who knows, may be true), but I think you're wrong on both points: The data is far from complete and I don't think Tefferi is fudging on it.

FWIW, Tefferi and my hematologist are clinicians who are really concerned about QoL issues, yet neither one likes Jakafi at all. I'm sure there are other views on this in the medical community. But when you talk about "items that matter most," what matters more than saving lives, and Jakafi doesn't do that. Imetelstat might. That's really the point here.

Bladerunner