I just talked to my personal hematologist. (He is friends with Tefferi.) He says that spleen size is "purely palliative" and overrated as an endpoint. He says Imetelstat will provide OS benefit, which Jakafi doesn't do. He has one patient in Tefferi's trial now and is trying to get more patients in. He wants them on Imetelstat.
I called another oncologist that I know. He has been buying GERN all morning. He says the results are "sensational" (his words) and that this will definitely become the go-to drug in MF.
I trust the practicing oncologists more that I trust Feuerstein, although I think his critique is worth consideration.
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