NotBob,
In light of Peregrine's less than forthcoming attitude, third party validation seems necessary at this point. Saying that bavituximab has synergies with other checkpoint therapies, is worthless considering the source. I find it comical that since PD-1 therapies coined the new term "checkpoint", Peregrine has "jumped the bandwagon" and taken "checkpoint" as their own.
Now it's GLOBAL CHECKPOINT!
And BTW, IMO, GLOBAL CHECKPOINT mimics what I described in an earlier post, and it doesn't cost $50,000 to tell you..
"add a combination of PD-1 therapeutics, and instead of a proliferation of "dumb" T-Cells, you have, thanks to Bavituximab, tumor specific T-Cells ready to attack a non-self environment. The proliferation becomes smart, and instead of autoantibodies being pathological, they work in conjunction to these therapeutics, and help the entire immune response become, stronger, longer, and non-pathogenic".
How about I coin a new catchphrase that reflects this theory, "THE GATEKEEPER"!
Remember, you read it here first. ALA SIERRA :)
Be original Peregrine..
All the best,
John
Disclaimer: Every post, and all my views are only speculative. Do not invest money or any other resources based on these post or opinions. Best of luck and do your own due diligence!