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Re: dewophile post# 165303

Thursday, 08/15/2013 8:27:35 PM

Thursday, August 15, 2013 8:27:35 PM

Post# of 257266
Yes, resistance and combinability are very important. And I believe simeprevir has been very good on both of these fronts. Look at prior combo data with sofosbuvir in nulls; data in combo with daclatasvir and also IDX719 due later this year and may still also be path forward in combo with Vertex's nuke, VX-135, particularly ex-U.S. Finally, there should be room to compete with competing sofosbuvir-based regimens on price, particularly given the significant amount GILD needs to recoup from its acquisition of VRUS.

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