All told, I think PTLA’s Betrixaban program is pretty close to being a scam.
FWIW I don't know doodly about most of your list and PTLA's sins in regards to it. I was just reacting to the original post about 35 days vs 10 days on Lovenox. Given the approval will undoubtedly be based upon both a comparison of VTE **and** bleeds I don't see PTLA picking of a different time point as particularly gamey. E.g. If a SOC VTE patient gets 14 days Lovenox and then 15 days oral (because injections are difficult at home) then it doesn't seem unreasonable to test that sequential-drug SOC against a single drug with a potentially lower rate of bleeds.
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