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Re: genisi post# 162930

Monday, 06/24/2013 6:12:20 AM

Monday, June 24, 2013 6:12:20 AM

Post# of 257301
PLX

On Enbrel - before attending PLX analyst day, I took another look at patent #8,063,182 and I'm quite certain the only possible way around it for PLX is with oral delivery. I later have asked their CEO if so, and from his answer I got the impression they will not go on with IV Enbrel.
On inhaled recombinant AAT - I have asked about the strategy to break KMDA's potential orphan exclusivity and the answer is as put by ghmm "being a recombinant product would convey some safety benefits" over the human plasma derived product. As discussed here before, I don't think this will work and I'm not even sure PLX will go on with this program if KMDA is successful in its clinical trial.

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