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Re: rkrw post# 20233

Monday, 12/12/2005 10:33:23 AM

Monday, December 12, 2005 10:33:23 AM

Post# of 257625
>Lessons from ptie: be very cautious of phase III trials based on flimsy phase II's (both oxytrex and the ibs drug). This mad rush to go into phase III can be reckless.<

I would temper that by saying that it depends on how well understood the treatment pathway is. For instance, DNA jumped directly from phase-1/2 to dual pivotal trials for Lucentis because the VEGF pathway was well understood (by them).

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