Someone posted a question earlier about how often do human clinical trials mirror preclinical work. I couldn't find anything in terms of efficacy between mouse and men but this caught my eye:
"Only about one drug in 10,000 actually makes it. However, due to the rigorous processes of preclinical research, about one in five drugs that get an IND eventually make it through trials." Link below.
That number for IND is actually much higher than I thought. And the nice thing about Kevetrin is that it was extensively tested in the preclinical setting. Not only that but preclinical work was so broad and showed efficacy across a range of cancers. Should note here that is says makes it through trials, not necessarily FDA approved.
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