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Re: DewDiligence post# 160021

Thursday, 04/18/2013 12:23:59 PM

Thursday, April 18, 2013 12:23:59 PM

Post# of 253250

he specificity of only 87% is problematic



I disagree with you here. Let's assume I could come up with a test that was only 50% specific, but close to 100% sensitive for polyps. Use of that test would cut the need for colonoscopies in half and greatly improve the overall testing system.

This is a very different application from those like prostate or breast cancer screening where a false-positive leads to a biopsy. Here the false positive simply leads to the same procedure you would have done anyway absent the test.

So the big disappointment for me (and it's personal given I am due a colonoscopy in the next year or two) is the low 42% sensitivity.

Peter
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