By his estimate, MANF would acquire 14% market share by 2025 after FDA approval in 2021.
The PD maket currently 3.5 Billion and lets say by 2027 it is close to 10 billion. But not all of market share is given to MANF because of competition such as CDNF, GDNF (if successful) and others. So company that is partnering with AMBS would get 14% of 10 billion. i.e 1.4 billion and AMBS would get royalty of 10% of it. i.e 140 mil.