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Re: DewDiligence post# 18851

Saturday, 11/19/2005 10:43:10 PM

Saturday, November 19, 2005 10:43:10 PM

Post# of 257297
Kerx: Hi Dew,

As I was saying from before, the trial is only 16.7% powered. When the trial 3 reaches 1000 pts, it will be 90% powered and
we can be more defenitive of the data.

From the power pt presentation, efficacy is clear. placebo:11% 200mg dose: 33%. They were 20 trials done in the process which proved the drug works. Also there were no sig side effects and no dose toxicities. I feel this drug might work to a certain extent and has a good chance for approval because the FDA's SPA endpoint is not very high. This will be a first mover and later others like speedel might better it.

But the cancer drug krx 401 is the one I am really interested in...It is a new class and the moa is very novel. I will keep this on the radar and once I know more abt 401 and 101, I will let you know.

Regards,
Dr.Praveen




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