biomaven0,
There are two biotech business models for drugs development:
1. Invent/discover its own drugs and
2. Acquire potential candidates(Amylin, ImClone, Mediviation, Millennium, etc.,)
There are also combinations of the two above (Genentech, etc.,). These approaches are all equally viable. Remember, any biotech is a commercial venture.
At the same time and in any cases, a company must be capable of designing and execution clinical trials for speediest regulatory approvals and maximized & successful marketing. If a company is incapable of designing & running successful clinical trials, the rest is very much pitiful. Such companies are failures regardless of their discovery capabilities.
PS
I have Celldex in my investment/trading portfolio.