RespireRx Pharmaceuticals Inc (RSPI)

[neuroinv]

I'm not totally convinced that there is an imminent wave of legalization and medicalization about to swamp the country. I know Washington and Colorado went to legalization, but California, the heartland of the medical marijuana movement, voted against legalization when it most recently was on the ballot. And in Southern California, most dispensaries have been shut down--there was a recent news report that not a single dispensary remains open in San Diego. It's cyclical, and it probably will end up with relatively open access, but the question of dispensary-provided THC as a competitor to dronabinol is among the least of Cortex's problems. If they are still around to worry about it, something else will have to go right.

As I have written before, the place something could (and should, but that doesn't mean much these days) go right, sooner rather than later, is in circumventing the effects of Respiratory Depression. Galleon's work that you cited--nice find on that PR--employs a s-nitrosylating mechanism associated with cardiovascular side effects. I don't know where they did this most recent trial, it wasn't in the US, and they are not going to find funding easily either.

NP