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Re: mcbio post# 154739

Tuesday, 01/01/2013 4:19:45 AM

Tuesday, January 01, 2013 4:19:45 AM

Post# of 257391

Yes, it's in Phase 1 now with data due in mid-2013 I believe.





ARWR is enrolling patients with castrate-resistant prostate cancer for this phase 1 obesity study. The whole thing seems rather strange. I would expect the drug to be tested first in obese patients without co-morbidities to get a clean read on the drugs safety profile. One of the primary outcome measures is disease progression. Talk about killing two birds with one stone.


ARWR's PR states



Fat tissue is known to produce substances that can promote prostate cancer growth






This is a cancer trial mislabeled as an obesity trial. Talk of follow-on formulations, and the design of this study, appears to suggest this drug won't be used within the general population nor partnered for the obesity indication.


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