Rawnoc----"RFA appeared safe and highly effective in tumor destruction depending on tumor size[23]. Importantly, the recurrence rate of 21.6% for tumors = 2.5 cm, 52.8% for tumors 2.6 - 4.0 cm in size and 68.8% for tumors larger than 4.1 cm have been reported[24], indicating a strong argument for RFA application in smaller tumors. The reviewed data today are not sufficient to judge whether RFA prolongs survival in patients with advanced colorectal liver metastases[23]. A prospective trial by our group[25] has shown an overall survival rate at 1, 2 and 3 years of 88%, 80% and 57% respectively."