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Tuesday, December 18, 2012 3:43:00 PM
This explains all you need to know about AMBS. It has patent protection on MANF which was upheld by Hermo Pharma who is quoted in the above article as saying that their patent protection causes an undue burden on anyone trying to work on MANF. Think about how powerful of a statement that is.
Then look at their valuation: $13 Million for something that has had much better results than GDNF which was owned by a company that was bought out for $250 Million by Amgen while GDNF was in the same stage of testing as MANF: pre-clinical trials. GDNF was halted due to poor delivery methods but it is currently revived in phase II trials because delivery methods have been vastly improved over the past 10 years.
Then look at the statement by the CO FOUNDER OF AMGEN: "I believe in MANF," said Dr. Rubinfeld, "I have reviewed a great number of technologies in my 45 year career in the biopharmaceutical field, and I believe that MANF could be one of the biggest successes that I have ever seen. The fundamental scientific premise of reducing protein misfolding is basic, yet very profound. The data, while early, demonstrates very clearly at the cellular level and in animals that MANF reduces apoptosis, improves cellular function, and restores behavioural deficits in a number of disease models, including Parkinson's, Stroke, Myocardial Infarction and Traumatic Brain Injury. These are all indications with very large markets and clear unmet medical need. I believe that if we are able to further de-risk MANF with positive toxicology studies and early clinical data, the Company's new orphan drug strategy could get MANF to market rather expeditiously. MANF has the commercial potential to become a blockbuster drug." This is a 79 year old man that started up Amgen, that invented Amoxicillin, and that founded Supergen.
Ask yourself:
(1) Should this be worth $13 Million when it is producing better results than another drug that received a $250 Million buyout?
(2) Should this be worth $13 Million when junk penny stocks like MJNA, TAGG, SPNG, GZFX at one point had $100-$175 Million market caps?
There is a reason why Hermo Pharma contested their patents and why the co-Founder of Amgen believes it could be the biggest success he has ever seen.
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