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Re: caravon post# 153844

Monday, 12/10/2012 10:10:55 PM

Monday, December 10, 2012 10:10:55 PM

Post# of 252581

"12 patients and 4 patients treated". Well it is not serious to discuss these PFS & mOS results unless there were many pts with objective and complete responses.

And I couldn't disagree more. Sure, these are results in a small number of patients that must be replicated in a larger trial and there are no guarantees of that. But you should also give CLDX some credit for showing stat sig results in a trial with such a small number of patients that wasn't even powered to detect statistical significance. I.e., the smaller number of patients in the trial should make it much more difficult to attain stat sig results yet the results were robust enough to do just that. Certainly merits disussion, at a minimum, IMHO.

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