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Re: p3analyze post# 153772

Saturday, 12/08/2012 2:15:05 PM

Saturday, December 08, 2012 2:15:05 PM

Post# of 257580

We know Pfs is correlated with OS and can be considered as a surrogate endpoint.

How do we know PFS is correlated with OS? I still don't understand where you're coming from here.

I don't buy it until cldx shows there is no bias in the process of subset ting.

Today's PR says the following: "Nearly all patients had Stage IV, or metastatic, disease. Patients on the CDX-011 arm received a median of six prior courses of therapy and patients on the IC arm received a median of five prior courses of therapy." That doesn't read to me as a bias in favor of the 011 arm.

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