I only have time to answer #5. You're right that this is phase I and for safety, but they have placed secondary outcomes for this trial that includes efficacy. One quote from someone I remember readin was "These guys aren't @&%*%ing around!" When he saw the Phase I trial write up. Don't make the same mistake other well known people are making. Spend a 1/2 hour of DD and you will easily find these answers and become a long. I would reccomend reading all of DrFeelgoods posts regarding CTIX and of course the stickies. GLTY