Thank you both for an excellent and informative exchange.
I did not catch Saltz's ASCO talk
I did only since Dew provided an old post with a link.
There is something in Dr. Saltz's talk that is very discouraging to me. He says maybe it's the diet that causes differences in tolerance of the drugs between Americans and Europeans. Could be, of course, as well as even differences in recording side effects.
But Europeans aren't Americans as a group and each within the group have individually different genetic heritage.
Personalized medicine obviously has a tough uphill climb when even a renowned doctor like Saltz makes so little concession to genetics.