That is a great chart mojo! And as you say it shows that Bavi INCREASES the amount of M1 macrophages by four fold compared to the amount seen in a normal tumour enviornment. But it also DECREASES the amount of M2 macrophages four fold.
So if we think of this as a football game prior to Bavi the pro-cancer team had 9 players against the 7 anti-cancer players. No wonder the cancer was winning.
After Bavi enters the fray the pro-cancer team is reduced to 2 players while the anti-cancer team is increased to 14. Now the MOS is doubled...and with better combinations cancer may even be wiped out!