Avid Bioservices Inc (CDMO)

[freethemice]

Mojojojo,
I'll send them to you. The "high" and "low" refer to the amount of the receptor proteins CD163 and CD204
that were detected on the surface of the tumor samples. A high amount of either of those two proteins is associated
with the M2-type macrophage. In both of these two studies the patients had mostly earlier stage pancreatic cancer
that was removed by surgery and tumor tissue samples stored for later. It was thought that the surgery might
cure them, but the survival curves show the cancer came back over time except for about 20-30% who had survived for 5 years.
So this is a retrospective look at the patients and an attempt to understand what factors were present that
distinguished long-term survivors from those who were not.
The details are that CD204 (SR-A) is a class A scavenger receptor, and CD163 (MR) is a mannose receptor.