"Temodar+radiation +/- Avastin; the HR for PFS was 0.64 (p<0.0001). Although the OS data are still maturing, they almost certainly won’t be statsig; at the most recent checkpoint, the HR for OS was 0.89 (p=0.21)." Early treatments benefits are in but then something did not go the Right Way. May be the combo is missing an additional treatment component?