Biotech Values

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MNTA European/U.S. Patent Applications Update for RMF - Plus MNTA Overview of their Patent Estate -

1.Methods related to cell surface glycosylation 2012-10-17

Abstract:
The present disclosure provides methods for assessing the glycosylation of a target glycoprotein produced by a cell through analysis of cell-surface glycans on the cell. The present disclosure therefore teaches that glycosylation of cell surface proteins can serve as a proxy for glycosylation of other proteins.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20121017&CC=EP&NR=2511705A1&KC=A1

2.ANTENNARY FUCOSYLATION IN GLYCOPROTEINS FROM CHO CELLS
2012-10-10

Abstract:
The present invention provides methods of evaluating CHO cells and producing recombinant glycoproteins.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&ND=3&adjacent=true&locale=en_EP&FT=D&date=20121010&CC=EP&NR=2507627A2&KC=A2

3.N-ACETYLHEXOSAMINE-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS 2012-09-20

Abstract:
The present invention provides methods of evaluating a glycoprotein preparation for the absence, presence or amount of an N-acetylhexosamine glycan, e.g., an N- acetylglucosamine glycan.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120920&CC=WO&NR=2012125553A2&KC=A2

4.GLYCOSYL TRANSFERASE FROM CHINESE HAMSTER AND RELATED METHODS 2012-09-19

Abstract not available

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120919&CC=EP&NR=2499245A2&KC=A2

5.EVALUATING HEPARIN PREPARATIONS 2012-08-30

Abstract:
Methods of evaluating heparin preparations, e.g., for suitability for use as a drug or for use in making a drug, by determining the absence, presence or amount of a structural signature, wherein, e.g., the structural signature is indicative of the methods used to make the heparin preparation.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=2&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120830&CC=WO&NR=2012115952A1&KC=A1

6.GLYCOSYL TRANSFERASE FROM CHINESE HAMSTER AND RELATED METHODS 2011-05-19

Abstract:
A glycosyl transferase from Chinese hamster and related methods are described.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20110519&CC=CA&NR=2778839A1&KC=A1

7.Heparan sulfate glycosaminoglycan lyase and uses thereof
2012-04-18

Abstract:
The invention provides recombinant B. thetaiotaomicron GAG lyase polypeptides. The invention also provides nucleic acid molecules encoding such polypeptides, recombinant expression vectors containing B. thetaiotaomicron GAG lyase nucleic acid molecules, and host cells into which the expression vectors have been introduced. Characterization, diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120418&CC=EP&NR=2441830A2&KC=A2

8.METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS 2012-04-11

Abstract:
Not available

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120411&CC=EP&NR=2438185A1&KC=A1

9.PRODUCTION OF GLYCOPROTEINS 2012-04-04

Abstract:
Not Available

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120404&CC=EP&NR=2435577A2&KC=A2

10.GALACTOSE-ALPHA-1, 3-GALACTOSE-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS

Abstract:
The present invention provides methods for evaluating a Chinese Hamster Ovary (CHO) cell population by measuring glycans containing terminal galactose-alpha-1-3-galactose residues produced by said cells, wherein the CHO cells have not been genetically engineered to express an alpha-galactosyl transferase coding sequence.

PATENTS

We license or own a patent portfolio of over 70 patent families, each of which includes United States patent applications and/or issued patents as well as foreign counterparts to certain United States patents and patent applications. Our patent portfolio includes issued or pending claims covering:

*Methods and technologies for characterizing polysaccharides and other heterogeneous mixtures

*The composition of matter and use of certain heparinases, heparinase variants and other enzymes

*Methods and technologies for synthesis of polysaccharides

*The composition of matter and use of certain novel low molecular weight heparin products, including M402

*Methods to identify, analyze and characterize glycoproteins

*Methods of manufacture of certain polysaccharide, polypeptide and complex protein or biologic products

http://www.momentapharma.com/technology/patents.php