Re: 15 best-selling drugs in 2012 A few comments: 1. Three of the top-4 drugs—comprising about $25B of sales—are from the TNF-a class, which is surely one of the main targets for FoB’s. 2. Plavix would have ranked near or at the top of the list if it had been on-patent for the entire year. 3. Oral anticoagulants, especially Eliquis, will be on the list in the next few years.