CHMP approves Tradjenta in combination with insulin: http://finance.yahoo.com/news/chmp-recommends-indication-trajenta-linagliptin-122000194.html Tradjenta, from a JV of LLY and B-I, was approved in the EU as a monotherapy in 2011 (#msg-64617999). In the US, Tradjenta is approved both as monotherapy and in combination with metformin (under the brand name, Jentadueto).