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Re: cjgaddy post# 90257

Thursday, 09/06/2012 10:19:09 AM

Thursday, September 06, 2012 10:19:09 AM

Post# of 347009
Great! 5.4 months for the control MOS, that makes the MOS for the treatment arms even better in comparison.
If less than 35% treatment arm patients had died by the end of April (is that when it was unblinded)
this could go on for a while. It could get to 3X the control arm MOS. The treatment arm patients may
be on a plateau if plotted on a KM survival curve. At some point you could say their cancer is controlled,
or cured. I think the emphasis on CRs is wrong because CRs are defined by the RECIST criteria and are
measured during the treatment cycles. It is possible to have a CR, as defined by those criteria, and then
to later progress and not be a CR. CR does not mean cure. On the other hand it can go the other way too.
We are now in a place where we don't really know what is going on inside those patients still alive, all we
know is that they are still alive.
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