Koch claims the sustained decrease in blood pressure with 797 treatment may actually be beneficial to the drug's profile. In pre-clinical animal models, ARRY has increased OS in CHF animal models with 797. Koch also mentioned that GSK has a p38 inhibitor in a trial for ACS. I believe this is the one: http://www.clinicaltrials.gov/ct2/show/NCT00910962?term=p38&recr=Open&rank=11