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Friday, 07/27/2012 5:52:17 PM

Friday, July 27, 2012 5:52:17 PM

Post# of 257253
MNTA European/U.S. Patent Applications Update for RMF - Plus MNTA Overview of their Patent Estate -

1.GLYCOSYL TRANSFERASE FROM CHINESE HAMSTER AND RELATED METHODS 2011-05-19

Abstract:
A glycosyl transferase from Chinese hamster and related methods are described.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20110519&CC=CA&NR=2778839A1&KC=A1

2.Heparan sulfate glycosaminoglycan lyase and uses thereof
2012-04-18

Abstract:
The invention provides recombinant B. thetaiotaomicron GAG lyase polypeptides. The invention also provides nucleic acid molecules encoding such polypeptides, recombinant expression vectors containing B. thetaiotaomicron GAG lyase nucleic acid molecules, and host cells into which the expression vectors have been introduced. Characterization, diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120418&CC=EP&NR=2441830A2&KC=A2

3.METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS 2012-04-11

Abstract:
Not available

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120411&CC=EP&NR=2438185A1&KC=A1

4.PRODUCTION OF GLYCOPROTEINS 2012-04-04

Abstract:
Not Available

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120404&CC=EP&NR=2435577A2&KC=A2

5.GALACTOSE-ALPHA-1, 3-GALACTOSE-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS

Abstract:
The present invention provides methods for evaluating a Chinese Hamster Ovary (CHO) cell population by measuring glycans containing terminal galactose-alpha-1-3-galactose residues produced by said cells, wherein the CHO cells have not been genetically engineered to express an alpha-galactosyl transferase coding sequence.

6.Methods of evaluating mixtures of polysaccharides 2012-01-24

Abstract:
Methods for analyzing mixtures of polysaccharides, for example heparin or a LMWH, using reduce end labeling are described. In general, the mixture of polysaccharides includes polysaccharides having a desired structural moiety. In some instances, one or more polysaccharides in the mixture are chemically modified prior to analysis.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120124&CC=US&NR=8101733B1&KC=B1

7.Low molecular weight heparin composition and uses thereof 2012-01-11

Abstract:
Preparations of low molecular weight heparins (LMWHs) having improved properties, e.g., properties that provide a clinical advantage, are provided herein. Methods of making and using such preparations as well as methods of analyzing starting materials, processing, intermediates and final products in the production of such LMWH preparations are provided.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&ND=3&adjacent=true&locale=en_EP&FT=D&date=20111028&CC=MX&NR=2011007545A&KC=A

8.METHODS OF ASSESSING ACTIVITY OF A POLYSACCHARIDE COMPOSITION 2012-02-22

Abstract:
Methods of assessing polysaccharide preparations lacking substantial anticoagulant activity are provided herein.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=2&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120222&CC=EP&NR=2419736A1&KC=A1

9.CONTROL OF COPOLYMER COMPOSITIONS 2012-02-08

Abstract:
Methods of making copolymers are described.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=3&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120208&CC=EP&NR=2414384A1&KC=A1

10.Analysis of sulfated polysaccharides 2012-01-04

Abstract:
The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=3&ND=3&adjacent=true&locale=en_EP&FT=D&date=20120104&CC=EP&NR=2402753A1&KC=A1


PATENTS

Over 100 patents give Momenta a strong proprietary position.

Momenta possesses a strong intellectual property position around our characterization platform. We license or own a total of over 100 patents and patent applications. Our patent portfolio includes claims covering:

•methods and technologies for characterizing sugars;
•the use of certain enzymes and reagents that specifically recognize polysaccharides in the characterization of sugars;
•methods and technologies for chemical and metabolic synthesis of sugars;
•the composition of matter of certain novel low-molecular-weight herapins (LMWHs), including M118, and heparinase variants;
•methods to produce and identify sugars associated with glycoproteins;
•methods to analyze and monitor glycoprotein profiles for purposes associated with the diagnosis, staging, prognosis and monitoring of cancer; and
•methods for the in vivo non-invasive delivery of sugars.

We also rely on trade secrets, know-how, continuing technological innovation and in-licensing opportunities to develop and maintain our proprietary position

http://www.momentapharma.com/technology/patents.html

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