SNTA - interesting paper that concludes progression caused by new mets is a much stronger predictor of OS than is tumor growth or tumor burden: http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail_view&confID=114&abstractID=98817 Note: 1) The effect appears in both CRC and in NSCLC - but looks stronger in NSCLC. 2) Obviously I consider this exploratory - but interesting enough to post here -g-.