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Re: acgood post# 133188

Saturday, 07/14/2012 3:09:11 PM

Saturday, July 14, 2012 3:09:11 PM

Post# of 257431

the MRK BACE program is indeed from Ligand. Phase 1 single dose showed the 58% reduction mentioned in LGND 10k, Phase 1 multidose showed 90% reduction (November 2011 MRK slides), and phase 2 to start 2012.

As is the case for numerous of their programs, Ligand knows nothing more than what MRK has put out publicly
.

Just to follow up on this, why doesn't LGND disclose this particular project in its pipeline on its Web site (http://www.ligand.com/pipeline )? Also, if you click on the "Collaborations" part of LGND's Web site and click on Merck (http://www.ligand.com/merck ), it only discloses a CDK inhibitor for cancer in Phase 2. Curiously missing on the entire Web site is the BACE inhibitor. Are we sure that the MRK BACE inhibitor is from LGND?

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