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Re: jq1234 post# 143555

Sunday, 06/10/2012 12:56:50 AM

Sunday, June 10, 2012 12:56:50 AM

Post# of 257302
ARQL -

I don't see why OS HR>0.8 is a big deal in this case. This is NSCLC against Tarceva not placebo. As long as stat significant, I really don't care if HR> or <0.8. Tarceva got approved with HR>0.8 against placebo.



I think a significant fraction of that ">0.8" is outright failure of the trial. And even if it gets, for instance, 0.83 it will be going against a MetMab label that says HR=0.5.

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