Heck, even CRIS/RHHBY got pushed through with a small 100 pt open-label Phase 2 in mBCC, aBCC. Certainly not unheard of, if they target a specific unmet pt population.
They need a real partner for this though; if they do it alone, I can really see them screwing this up badly - heck, they couldnt even check the right box at ASCO.