In addition, in patients with triple negative breast cancer who also highly express GPNMB, greater activity was observed (CDX-011 ORR of 36%; IC ORR of 0%)
In patients with both triple negative breast cancer and high GPNMB expression, a statistically significant PFS benefit is currently observed (p=0.0032)
(Caution these subgroup numbers are very small).
Not slam-dunk results, but pretty intriguing - stock is down a bit AH so who knows what the market was hoping for.
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