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NP1986

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NP1986

Re: iwfal post# 142408

Wednesday, 05/23/2012 12:44:03 AM

Wednesday, May 23, 2012 12:44:03 AM

Post# of 257681

Agreed - but it is an interesting and non-intuitive effect. Damaging the OS I can understand (via toxicity to patient), but accelerated tumor growth commonly occurring across the meta-class is just very counter intuitive to me.



Toxicity could also explain the effect on PFS, if it leads to early treatment discontinuation.

Treatment-related deaths would also be counted as an event for PFS, wouldn't they?
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