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genisi

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genisi

Re: genisi post# 131091

Monday, 05/21/2012 2:39:16 PM

Monday, May 21, 2012 2:39:16 PM

Post# of 252254

Given the significant reduction in death and the absolute major bleeding rates, I think the 2.5mg rivaroxaban dose has a good risk/reward profile in ACS.

Karen A. Hicks, M.D., the FDA reviewer seems to agree with this. From page 16 in the briefing docs:

I recommend approval of XARELTO® (2.5 mg po BID) to reduce the risk of cardiovascular events in patients with acute coronary syndrome (ACS)
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