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Re: vinmantoo post# 141369

Sunday, 05/06/2012 5:16:31 PM

Sunday, May 06, 2012 5:16:31 PM

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I wold be pretty surprised if SNTA made a substantial effort to use Ganetespib as a single agent in future trials.



That is exactly what they are doing though. The company is sponsoring single agent trials in both ALK lung and HER2/TN breast cancer - they definitely believe hsp90 inhibition is viable in biomarker defined populations.

My instincts tell me this is an active drug, but in my view it belongs in the hands of a big pharma. Whether any big pharma will agree with me or not is the basic investment decision here in my view.



Agree, this is a drug screaming for a buyout. Even a huge Asian partnership will not fund the trials that need to be run. Based on them not taking a regional deal to this point, I think the odds of a buyout increase, perhaps after docetaxel data at ESMO and potential ALK data at NCI-AACR-EORTC in the fall. This corresponds to about when they will be out of cash too. CFO answered a question on the call basically by saying "if we have a phase 3 ready unencumbered oncology asset, we'll have plenty of options"

Opinions and comments may have been previously posted @BioDueDiligence, at www.biotechduediligence.com, or disseminated to Chimera Research Group subscribers.

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