B-raf is a protooncogene that becomes over methylated in colorectal cancer cells. It also become hypermehtylated with age. For patients <75 BRAF methylation is a good screening tool, but not for patients >75.
Thanks for the clarification. So, how was the ColoGuard assay modified to account for the above?
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”