Avid Bioservices Inc (CDMO)

[entdoc]

RRdog, I'm not certain paclitaxel and carboplatin, being anti-mitotic, i.e inhibitory to rapid cellular division, are necessarily "somewhat apoptotic,"as you assert, but maybe. Don't remember seeing that in the package insert anyway. It is such a shame Bavi must be used with such losers as pacli- and carbo-, and oxy and toxi, because Bavi's "uregulation of the immune system" consists, in part, of goading the body to rapidly reproduce specialized immune-system cells, monocytes (body garbage collectors). Unfortunately the anti-mitotic chemotherapeutic agents the decrease cellular production probably have a "down-regulatory" effect on Bavi mechanism of action. I think I have seen that dilemma in print, and posted it here a few weeks ago.
The end of the Bavi narrative imo is that, in some iteration, Bavi will almost certainly be used to upregulate the immune system--Bavi-in-your-tea, or a Bavi nasal spray--aimed at micro-sepsis and micro-tumors. Chimeric Bavi is already last year's flavor (compared to Affitech's all-human Bavi). And our naked and chimeric Bavi isn't even through trials yet. I repeat. What a monstrous mistake Bavi trials did not commence with Bavi + irradiation therapy, or surgery. Now THERE you've got sumpin'!