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Re: ghmm post# 137369

Sunday, 02/19/2012 12:38:12 PM

Sunday, February 19, 2012 12:38:12 PM

Post# of 257262

I am just looking at them now. Is the stock price movement the past two months more because of their Gout data or HCV? I just see data with their Gout drug with allopurinol do you know if they have any monotherapy data?

I have really only taken a closer look of late myself, given the HCV nuke news. There was a small pop on the HCV news (I think 10%) so anything beyond that was presumably due to the gout drug.

In terms of the gout drug, I believe their plan is develop their gout drug in combo with allopurinol. The Phase 2b trial was a controlled trial comparing the BCRX drug plus allopurinol to placebo plus allopurinol. Efficacy (uric acid level below a certain level) was nearly doubled in the BCRX arm, though gout flares were a bit higher in the BCRX arm (5% for placebo vs. 7-16% in BCRX drug arms).

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