I have 2 HD.. primary one is 40 GB and secondary is 80GB, partioned in 2.. These are not RAIDs.. I use Ghost (I have Norton Systemworks Pro which comes with Ghost).. Basic backup strategy is to just take an image of primary HD to 1st partion of 2nd HD..
I am told by friends who have recovered, that Ghost works like a charm.. However, user interface to backup sucks..