R&D Spending* Per New Drug The following is an edited version of the table from Matt Herper’s article in Forbes (http://www.forbes.com/sites/matthewherper/2012/02/10/the-truly-staggering-cost-of-inventing-new-drugs ). The numbers are based on cumulative results during the 15-year period from 1997-2011 inclusive; the table rankings are in descending order of R&D productivity.[pre] Cumulative # New R&D Per R&D Expenses Drugs New Drug AMGN $33B 9 $3.7B NVS 84 21 4.0 BMY 46 11 4.2 MRK 67 16 4.2 ABT 36 8 4.5 LLY 50 11 4.6 JNJ 88 15 5.9 PFE 108 14 7.7 Roche‡ 86 11 7.8 SNY 63 8 7.9 GSK 82 10 8.2 AZN 59 5 11.8[/pre] *Including the cost of failed programs. ‡Includes DNA’s new drugs licensed by Roche and a pro-rata share of DNA’s R&D while majority owned by Roche.