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Re: DewDiligence post# 136239

Thursday, 02/02/2012 6:18:40 AM

Thursday, February 02, 2012 6:18:40 AM

Post# of 257442
Tau pathology spread in AD

The idea isn't new. One group showed evidence in-vitro and wrote: "We hypothesize that extracellular Tau aggregates can transmit a misfolded state from the outside to the inside of a cell, similar to prions."

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676015/?tool=pubmed

And these groups showed the spread of tauopathy from cell to cell in the brains of tau transgenic mice by injecting brain samples in two mice strains:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726961/?tool=pubmed

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