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Re: iwfal post# 135445

Saturday, 01/21/2012 6:43:40 PM

Saturday, January 21, 2012 6:43:40 PM

Post# of 257377
Have you done any of the looking at historical rates of ORR in such a highly refractory population?

If you are not counting GNMBP status then I can find very similar trials, and that is were I guessed 5% from.

I have no clue at all about how G+ selection would affect this. I do see cites that it is associated with outcomes (G+ has worse outcomes), but no sites on ORR.

EDIT: The Eribulan P3 trial was close in patient pool, and the comparator arm ORR was 5%.

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