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BTH

Re: poorgradstudent post# 135164

Monday, 01/16/2012 11:16:04 PM

Monday, January 16, 2012 11:16:04 PM

Post# of 257375

Rindopepimut is simply a 13 amino acid peptide attached to a carrier protein (KLH in this case). So the body has to ramp up an immune response against this peptide. This has historically been a relatively failing proposition in producing an adaptive immune response: you get low titre B-cell derived antigen specific antibodies and a weak T cell response. This is very similar to BLP25.



Is there any way these two drugs you mention are doing something to the tumor, despite not ramping a very strong T cell response?

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